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ATF-2 Polyclonal Antibody, 50ul[BT-AP00696] Deep Well Plates The encoded protein is located

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ATF-2 Polyclonal Antibody, 50ul[BT-AP00696] Deep Well Plates The encoded protein is locatedATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein (activating transcription factor 2) has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c Jun and stimulates CRE dependent transcription. This

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Description

The encoded protein is located in the Xq28 region and is arranged in a compact head-to-head manner with the isocitrate dehydrogenase 3 (NAD+) gamma gene and both genes are driven by a CpG-embedded bidirectional promoter

is a 2694 amino acid protein that belongs to the WD repeat Neurobeachin family

ontributes to the organization of the actin cytoskeleton and cell shape (PubMed: 21296879)

An important paralog of this gene is G3BP1

this interaction is however not essential for corepressor activity (By similarity)

ATF-2 Polyclonal Antibody, 50ul[BT-AP00696] Deep Well Plates The encoded protein is locatedATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein (activating transcription factor 2) has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c Jun and stimulates CRE dependent transcription. This

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