LRRK2 Polyclonal Antibody, 100ul Cell fragmentation and collection The 700-kD eukaryotic translation initiation

The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits

The protein belongs to the S21E family of ribosomal proteins

and maps to human chromosome 17q21

This protein causes differentiation of brain cells

The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin

LRRK2 Polyclonal Antibody, 100ul Cell fragmentation and collection The 700-kD eukaryotic translation initiationThis gene is a member of the leucine rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine rich repeat (LRR) domain, a kinase domain, a DFG like motif, a RAS domain, a GTPase domain, a MLK like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease 8.