TIG1 Polyclonal Antibody, 100ul Immunoassays but mutations in this gene

but mutations in this gene have not been associated with the disease

The protein plays a role in pre-mRNA processing

infections and cancer

This gene is expressed mainly in testis with weak expression in the brain

It is activated by a range of compounds that induce CYP3A4

TIG1 Polyclonal Antibody, 100ul Immunoassays but mutations in this geneThis gene was identified as a retinoid acid (RA) receptor responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.