SLP-76(Phospho-Tyr145) Rabbit Polyclonal Antibody, 100ul Sampling Tubes and interferon (IFN)-gamma

and interferon (IFN)-gamma

Low expression of the antigen results in impaired immune response

The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA)

and may play a role in vascular

using a separate promoter in an intron in the 3' region

SLP-76(Phospho-Tyr145) Rabbit Polyclonal Antibody, 100ul Sampling Tubes and interferon (IFN)-gammaSLP 76 was originally identified as a substrate of the ZAP 70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP 76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2 terminus contains an acidic