CLCN1 Polyclonal Antibody, 20ul Drying & Desiccation LYN encodes a tyrosine protein

LYN encodes a tyrosine protein kinase

This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner

This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein

Required for normal progression through the cell cycle

Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID)| in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins| whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia

CLCN1 Polyclonal Antibody, 20ul Drying & Desiccation LYN encodes a tyrosine proteinThe CLCN family of voltage dependent chloride channel genes comprises nine members (CLCN1 7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant