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NR1H4 Polyclonal Antibody, 100ul Dry Bath Mice deficient for this gene

SKU: 93326373977

4.5
SEK141.00 SEK168.00

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NR1H4 Polyclonal Antibody, 100ul Dry Bath Mice deficient for this geneThis gene encodes a ligand activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described.

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Description

Mice deficient for this gene have increased fat mass despite decreased food intake

Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2

This gene encodes a member of the tyrosine kinase and| more specifically| the Janus kinases (JAKs) protein families

MYL3 encodes myosin light chain 3

This enzyme functions as a cell surface receptor for bile acids

NR1H4 Polyclonal Antibody, 100ul Dry Bath Mice deficient for this geneThis gene encodes a ligand activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described.

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