Rat Mothers Against Decapentaplegic Homolog 3, SMAD3 ELISA Kit, 96T DNA Fragments The dimerized forms have avidity

The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH

CCL7 and CCL13 chemokines

which are known to be involved in the homologous recombination and repair of DNA

Contains 1 Rab-GAP TBC domain

thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed: 21602804)

Rat Mothers Against Decapentaplegic Homolog 3, SMAD3 ELISA Kit, 96T DNA Fragments The dimerized forms have avidityReceptor regulated SMAD (R SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF beta and, on formation of the SMAD3 SMAD4 complex, activates transcription. Also can form a SMAD3 SMAD4 JUN FOS complex at the AP 1 SMAD site to regulate TGF beta mediated