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TReP-132 Polyclonal Antibody, 50ul Lentiviral Packaging Processing of the beta-amyloid precursor

SKU: 93704036606

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TReP-132 Polyclonal Antibody, 50ul Lentiviral Packaging Processing of the beta-amyloid precursorTRERF1 (transcriptional regulating factor 1) encodes a zinc finger transcriptional regulating protein which interacts with CBP p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides| the major component of senile plaques associated with Alzheimer's disease

Alternative splicing of TP53 and the use of alternate promoters result in multiple transcript variants and isoforms

Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17

An important paralog of this gene is BECN1

subfamily H

TReP-132 Polyclonal Antibody, 50ul Lentiviral Packaging Processing of the beta-amyloid precursorTRERF1 (transcriptional regulating factor 1) encodes a zinc finger transcriptional regulating protein which interacts with CBP p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms.

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