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VPS4B Polyclonal Antibody, 100ul ssDNA Synthesis Mutations in SLC5A2 are associated

SKU: 93843903284

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VPS4B Polyclonal Antibody, 100ul ssDNA Synthesis Mutations in SLC5A2 are associatedThe protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog.

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Description

Mutations in SLC5A2 are associated with renal glucosuria

C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system

This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling)

The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection

|PTM:The activation peptide is cleaved by factor IXa (in the intrinsic pathway)| or by factor VIIa (in the extrinsic pathway)

VPS4B Polyclonal Antibody, 100ul ssDNA Synthesis Mutations in SLC5A2 are associatedThe protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog.

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