FAK Polyclonal Antibody, 100ul[BT-AP03136] Shakers This protein cleaves and activates

This protein cleaves and activates caspases 3 and 7| and the protein itself is processed by caspase 8

It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand

This gene encodes a replication-independent histone that is a member of the histone H2A family

It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates

The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis

FAK Polyclonal Antibody, 100ul[BT-AP03136] Shakers This protein cleaves and activatesPTK2 encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. Focal adhesion kinase 1 is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal