Tau(Phospho-Ser416) Rabbit Polyclonal Antibody, 50ul Bottles Mutations in this gene are

Mutations in this gene are associated with several congenital defects

and Liddle syndrome

So far detected are isoform Alpha-6X1A| isoform Alpha-6X1B and isoform Alpha-6X1X2A (minor)

The encoded protein is a neuron-specific| serine/threonine and tyrosine kinase| which regulates phosphorylation of tau| a protein that associates with microtubule assemblies and stabilizes them

subcellular location:Associated with axons of neuronal cells

Tau(Phospho-Ser416) Rabbit Polyclonal Antibody, 50ul Bottles Mutations in this gene areThis gene encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex regulated alternative splicing giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease Pick's disease frontotemporal dementia cortico