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SNAI 1(Phospho Ser246) Polyclonal Antibody, 20ul High Speed Micro-Centrifuges form a cytokine receptor gene

SKU: 947295396

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SNAI 1(Phospho Ser246) Polyclonal Antibody, 20ul High Speed Micro-Centrifuges form a cytokine receptor geneThe Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.

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Description

form a cytokine receptor gene cluster in a region mapped to chromosome 2q12

Myeloid differentiation primary response protein MyD88 functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways

Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation

The fibroblast activation protein alpha encoded by FAP is a homodimeric integral membrane gelatinase belonging to the serine protease family

and candidate gene studies suggest that genetic variation in this gene is associated with Alzheimer's disease

SNAI 1(Phospho Ser246) Polyclonal Antibody, 20ul High Speed Micro-Centrifuges form a cytokine receptor geneThe Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.

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