Tuberin/TSC2(Phospho-Ser1387) Rabbit Polyclonal Antibody, 20ul Mini dry bath Tumorigenesis may occur when this

Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles

This protein is essential for the folding and assembly of newly imported proteins in the mitochondria

cyclosporin A

subcellular location:Upon EGF stimulation

All family members contain the conserved acyl-Coenzyme A binding domain| which binds acyl-CoA thiol esters

Tuberin/TSC2(Phospho-Ser1387) Rabbit Polyclonal Antibody, 20ul Mini dry bath Tumorigenesis may occur when thisMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.