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In addition| the CXXC domain of this protein has been shown to bind unmethylated CpG dinucleotides| localize to promoters and CpG islands| and interact with the catalytic domain of methylcytosine dioxygenase ten-eleven-translocation 2| an iron and alpha-ketoglutarate-dependent dioxygenase that modifies the methylation status of DNA

The MutL-alpha heterodimer possesses an endonucleolytic activity that is activated following recognition of mismatches and insertion/deletion loops by the MutS-alpha and MutS-beta heterodimers

the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes

Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II

IRX2 Polyclonal Antibody, 50ul DNA Fragments Unlock DNA for new discoveriesIRX2 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.