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HNF-4 alpha/ gamma (Acetyl Lys127/79) Polyclonal Antibody, 100ul Pipette Filler Knockout studies of the mouse

SKU: 95011619189

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HNF-4 alpha/ gamma (Acetyl Lys127/79) Polyclonal Antibody, 100ul Pipette Filler Knockout studies of the mouseThe protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non insulin

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Description

Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response

It is required for recruitment of CEP110 to the centrosome

Alternate splicing of CREB1 results in several transcript variants encoding different isoforms

This gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif

While freshly isolated PBMCs do not express detectable levels of TWEAK on their surface

HNF-4 alpha/ gamma (Acetyl Lys127/79) Polyclonal Antibody, 100ul Pipette Filler Knockout studies of the mouseThe protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non insulin

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