IGF-IR Monoclonal Antibody, 50ul[BT-MCA0099] Live Cell Imaging multiple putative phosphorylation sites

multiple putative phosphorylation sites

TOP2B encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in TOP2B have been associated with the development of drug resistance

and thus mediates the nuclear translocation and mitogenic activity of the FGF2

Alternative splicing results in multiple variants

CD33 (MIM 159590))

IGF-IR Monoclonal Antibody, 50ul[BT-MCA0099] Live Cell Imaging multiple putative phosphorylation sitesThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have