YMEL1 Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation This gene encodes a protein

This gene encodes a protein localized in mitochondria and closely related to paraplegin

induction:By TP53/p53

and share DNA-binding

Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix

Three transcript variants that encode distinct proteins have been identified

YMEL1 Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation This gene encodes a proteinThe protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene.