CRADD Polyclonal Antibody, 20ul Thermal Control 100% passing rate for production
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CRADD Polyclonal Antibody, 20ul Thermal Control 100% passing rate for productionThis gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2 ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1 RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants.
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