NUDC3 Polyclonal Antibody, 20ul ROS/Nitric Oxide Detection Mutations in this gene are

Mutations in this gene are associated with spondylepiphyseal dysplasia and humerospinal dysostosis

The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa

The encoded protein contains several KH domains

The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin

it is probably inactive as an hydrolase due to lack of the conserved zinc-binding and active sites

NUDC3 Polyclonal Antibody, 20ul ROS/Nitric Oxide Detection Mutations in this gene areThe product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma tubulin from spindle poles. The protein localizes to the Golgi apparatus during interphase, and levels of the protein increase after the G1 S