NF-κB p105(Phospho-Ser933) Rabbit Polyclonal Antibody, 100ul Vortex Mixer Upon erythropoietin binding

Upon erythropoietin binding

Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix

TFRC encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis

It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction

A pseudogene of this gene is located on the long arm of chromosome 4

NF-κB p105(Phospho-Ser933) Rabbit Polyclonal Antibody, 100ul Vortex Mixer Upon erythropoietin bindingThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF kappa B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra and extra cellular stimuli such as cytokines oxidant free radicals ultraviolet irradiation and