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UBC Rabbit Polyclonal Antibody, 50ul Cryogenic Vials in a non-redundant way with

SKU: 95549363141

4.8
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UBC Rabbit Polyclonal Antibody, 50ul Cryogenic Vials in a non-redundant way withThis gene represents a ubiquitin gene ubiquitin C. The encoded protein is a polyubiquitin precursor. Conjugation of ubiquitin monomers or polymers can lead to various effects within a cell depending on the residues to which ubiquitin is conjugated. Ubiquitination has been associated with protein degradation DNA repair cell cycle regulation kinase modification endocytosis and regulation of other cell signaling pathways.

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Description

in a non-redundant way with ZFPM2/FOG2

The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila

spindle orientation

Expansion of a GGGGCC repeat from 2-22 copies to 700-1600 copies in the intronic sequence between alternate 5' exons in transcripts from this gene is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID: 21944778

It plays a putative role in tumorigenic reversion and may control cell proliferation

UBC Rabbit Polyclonal Antibody, 50ul Cryogenic Vials in a non-redundant way withThis gene represents a ubiquitin gene ubiquitin C. The encoded protein is a polyubiquitin precursor. Conjugation of ubiquitin monomers or polymers can lead to various effects within a cell depending on the residues to which ubiquitin is conjugated. Ubiquitination has been associated with protein degradation DNA repair cell cycle regulation kinase modification endocytosis and regulation of other cell signaling pathways.

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