Human Toll-like Receptor 7, TLR7 ELISA Kit , 96T In vitro Assessment it is normally found in

it is normally found in the nucleus except during mitosis

tissue specificity:Expression largely restricted to adipose tissue and spleen

May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin

one in cytosol and one in mitochondria

such as SCN11A

Human Toll-like Receptor 7, TLR7 ELISA Kit , 96T In vitro Assessment it is normally found inEndosomal receptor that plays a key role in innate and adaptive immunity (PubMed: 14976261, PubMed: 32433612). Controls host immune response against pathogens through recognition of uridine containing single strand RNAs (ssRNAs) of viral origin or guanosine analogs (PubMed: 31608988, PubMed: 27742543, PubMed: 12738885). Upon binding to agonists, undergoes dimerization that brings TIR domains from the two molecules into direct contact, leading to the