ACATN Polyclonal Antibody, 100ul Mammalian Expression Mutations in DDX3Y result in

Mutations in DDX3Y result in male infertility

This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide

It is involved in a diverse array of cellular functions| including ER-to-Golgi transport| the centripetal movement of lysosomes and endosomes| spindle formation| cytokinesis| chromosome movement| nuclear positioning| and axonogenesis

induction and maintenance of pluripotency

Depletion of this protein was noted in patients with Huntington disease

ACATN Polyclonal Antibody, 100ul Mammalian Expression Mutations in DDX3Y result inThe protein encoded by this gene is required for the formation of O acetylated (Ac) gangliosides. The encoded protein is predicted to contain 6 to 10 transmembrane domains and a leucine zipper motif in transmembrane domain III. Defects in this gene have been reported to cause spastic paraplegia autosomal dominant type 42 (SPG42) in one Chinese family but not in similar patients of European descent. Two transcript variants encoding the same protein