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I12R2 Polyclonal Antibody, 20ul Protein Post-translational Modification as well as other complex

SKU: 95640678357

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I12R2 Polyclonal Antibody, 20ul Protein Post-translational Modification as well as other complexThe protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up regulation of this gene is

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Description

as well as other complex processes

MIM 602916)

May act by regulating members of the CLK kinase family

This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration

This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis

I12R2 Polyclonal Antibody, 20ul Protein Post-translational Modification as well as other complexThe protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up regulation of this gene is

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