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Gas8 Polyclonal Antibody, 100ul Cell Screening and Imaging TSN encodes a DNA-binding protein

SKU: 95677764712

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Gas8 Polyclonal Antibody, 100ul Cell Screening and Imaging TSN encodes a DNA-binding proteinGAS8 includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16 or f3, that is transcribed in the opposite orientation. GAS8 is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene.

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Description

TSN encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations

LIM domain transcription factor LMO4 may play a role as a transcriptional regulator or as an oncogene

Two other peptides

ANKRD20A1 (Ankyrin Repeat Domain 20 Family Member A1) is a Protein Coding gene

The E74 like ETS transcription factor 1 is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes

Gas8 Polyclonal Antibody, 100ul Cell Screening and Imaging TSN encodes a DNA-binding proteinGAS8 includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16 or f3, that is transcribed in the opposite orientation. GAS8 is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene.

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