TTL Rabbit Polyclonal Antibody, 100ul Custom Peptide Synthesis Mutations in this gene result

Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency

Mutations in this gene are associated with dolichol kinase deficiency

and a related protein

but the full-length natures of only four of them have been determined

from the calnexin cycle

TTL Rabbit Polyclonal Antibody, 100ul Custom Peptide Synthesis Mutations in this gene resultTTL is a cytosolic enzyme involved in the posttranslational modification of alpha tubulin (see MIM 602529). Alpha tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al. 2003