CCAR1 Polyclonal Antibody, 100ul Bacterial Expression This gene is a member

This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24

The testis-specific serine/threonine-protein kinase 4 is thought to be involved in spermatogenesis via stimulation of the CREB/CRE responsive pathway through phosphorylation of the cAMP responsive element binding protein transcription factor

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differ in the number of N-terminal zinc finger motifs that bind DNA and in nuclear localization signal presence

Mutations in this gene are associated with Nijmegen breakage syndrome| an autosomal recessive chromosomal instability syndrome characterized by microcephaly| growth retardation| immunodeficiency| and cancer predisposition

CCAR1 Polyclonal Antibody, 100ul Bacterial Expression This gene is a memberMay be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14 3 3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and or cell proliferation.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence Contaminating sequence. Potential poly A sequence.,Contains 1 SAP