UBP18 Rabbit Polyclonal Antibody, 100ul Cell Dissociation This gene encodes a CREB

This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane

along with actin microfilaments and microtubules

and its inactivation may contribute to meningioma 32 pathogenesis

Binding of its ligand

Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival

UBP18 Rabbit Polyclonal Antibody, 100ul Cell Dissociation This gene encodes a CREBThe protein encoded by this gene belongs to the ubiquitin specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin like protein) fusions and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues indicating that this protein is a major