Zic1/2/3/4/5 Polyclonal Antibody, 50ul Cell Senescence It is a transcriptional repressor

It is a transcriptional repressor of genes that require a bHLH protein for their transcription

CLIP2 is hemizygously deleted in Williams syndrome

which is an upstream activator of both p38 and JNK MAPKs

subunit:Interacts with actin monomer

a system implicated in the pathogeny of such psychiatric diseases as depression

Zic1/2/3/4/5 Polyclonal Antibody, 50ul Cell Senescence It is a transcriptional repressorZIC1 (Zic family member 1) encodes a member of the ZIC family of C2H2 type zinc finger proteins. Members of this family are important during development. Aberrant expression of ZIC1 is seen in medulloblastoma, a childhood brain tumor. ZIC1 is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. ZIC1 encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.