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PP4R2 Polyclonal Antibody, 50ul Oligo Pool subunit:Isoform 2 interacts with CASP2

SKU: 95910799339

4.1
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PP4R2 Polyclonal Antibody, 50ul Oligo Pool subunit:Isoform 2 interacts with CASP2Serine threonine protein phosphatase 4 regulatory subunit 2 encoded by PPP4R2 is a regulatory subunit of the serine threonine protein phosphatase 4 complex. In addition to being required for efficient DNA double strand break repair, this complex plays a role in organization of microtubules at centrosomes and processing of spliceosomal snRNPs. Several transcript variants encoding different isoforms have been found for this gene.

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Description

subunit:Isoform 2 interacts with CASP2 and CASP9

Mutations in this gene have been associated with primary microcephaly (MCPH4)

The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation

Mutations in PNPT1 have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70

Heat shock protein 105 kDa prevents the aggregation of denatured proteins in cells under severe stress

PP4R2 Polyclonal Antibody, 50ul Oligo Pool subunit:Isoform 2 interacts with CASP2Serine threonine protein phosphatase 4 regulatory subunit 2 encoded by PPP4R2 is a regulatory subunit of the serine threonine protein phosphatase 4 complex. In addition to being required for efficient DNA double strand break repair, this complex plays a role in organization of microtubules at centrosomes and processing of spliceosomal snRNPs. Several transcript variants encoding different isoforms have been found for this gene.

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