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CD58 Polyclonal Antibody, 50ul[BT-AP02070] In vitro Transcription This I-domain containing alpha integrin

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CD58 Polyclonal Antibody, 50ul[BT-AP02070] In vitro Transcription This I-domain containing alpha integrinCOL18A1 (collagen type XVIII alpha 1 chain) encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple helix domains (collagenous domains) interrupted by non collagenous domains. A long isoform of the protein has an N terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in

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Description

This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1')

which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway

It is expressed in a tissue-specific manner in the liver| colon| and intestine

Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms

and cell adhesion

CD58 Polyclonal Antibody, 50ul[BT-AP02070] In vitro Transcription This I-domain containing alpha integrinCOL18A1 (collagen type XVIII alpha 1 chain) encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple helix domains (collagenous domains) interrupted by non collagenous domains. A long isoform of the protein has an N terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in

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