NPHP3 Rabbit Polyclonal Antibody, 50ul Glassware The protein encoded by this

The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains

ultimately influencing mitogenesis and differentiation

and a WD40 domain

|Belongs to the serine esterase family

which are required for its enzymatic function

NPHP3 Rabbit Polyclonal Antibody, 50ul Glassware The protein encoded by thisThis gene encodes a protein containing a coiled coil (CC) domain a tubulin tyrosine ligase (TTL) domain and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin it is required for normal ciliary development and it functions in renal tubular development. Mutations in this gene are associated with nephronophthisis type 3 and also with renal hepatic pancreatic dysplasia and Meckel syndrome type 7. Naturally occurring