LFTY2 Rabbit Polyclonal Antibody, 50ul Electronic Pipette Interleukin-7 receptor subunit alpha encoded

Interleukin-7 receptor subunit alpha encoded by IL7R is a receptor for interleukin 7 (IL7)

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It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity

Mutations in this gene are associated with Joubert syndrome-22

Biochemical and genetic data suggest a role as a tumor suppressor

LFTY2 Rabbit Polyclonal Antibody, 50ul Electronic Pipette Interleukin-7 receptor subunit alpha encodedThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein which plays a role in left right asymmetry determination of organ systems during development. The