MIB2 Polyclonal Antibody, 50ul Yeast Expression Also highly expressed in ovarian

Also highly expressed in ovarian and leukemia cell lines

Mutations in SLC4A11 have been associated with a number of endothelial corneal dystrophies including recessive corneal endothelial dystrophy 2

The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle

POLD3 encodes the 66-kDa subunit of DNA polymerase delta

such as ZNF272

MIB2 Polyclonal Antibody, 50ul Yeast Expression Also highly expressed in ovarianE3 ubiquitin protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.,induction: Down regulated in many primary skin melanomas. Treatment with a demethylating agent, 5' aza 2 deoxycytidine, restores expression, suggesting that down regulation is the result