RFX6 Rabbit Polyclonal Antibody, 20ul Vessels One important function of uracil-DNA

One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway

and structural properties

which encodes TFIIA-alpha/beta-like factor

maps to chromosome 6p21

It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes

RFX6 Rabbit Polyclonal Antibody, 20ul Vessels One important function of uracil-DNAThe nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin but not for the differentiation of pancreatic polypeptide producing cells. It regulates the transcription factors involved in beta cell maturation and function thus restricting the expression of the beta