RNF138 Polyclonal Antibody, 100ul Recombinant Protein were originally characterized based on

were originally characterized based on their interaction with the Stat family of transcription factors

this step is thought to be one of the earliest in the caspase activation cascade

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Binding of 53BP1 to the L3 loop of p53 and of 53BP2 to the L2 loop of p53 confirms that the loop is dependent on p53 conformation

thus reducing the number of supercoils and altering the topology of DNA

RNF138 Polyclonal Antibody, 100ul Recombinant Protein were originally characterized based onThe protein encoded by RNF138 (ring finger protein 138) contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein DNA and protein protein interactions. Alternatively spliced transcript variants encoding distinct isoforms have been observed.