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Acetyl p53 (K319) Polyclonal Antibody, 100ul Stepper and deletions at this locus

SKU: 96548064957

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Acetyl p53 (K319) Polyclonal Antibody, 100ul Stepper and deletions at this locusTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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Description

and deletions at this locus are also associated with a decrease in aminoacylase activity

belonging to the glycogen synthase kinase subfamily

lung and peripheral blood leukocytes

protecting cells from oxidative stress

NAALADase cleaves N-acetyl-L-aspartate-L-glutamate (NAAG)| which is a neuropeptide expressed both in the central nervous systems and in the periphery and is thought to function as a neurotransmitter

Acetyl p53 (K319) Polyclonal Antibody, 100ul Stepper and deletions at this locusTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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