FoxN4 Polyclonal Antibody, 50ul Culture Tubes An important paralog of NPY2R

An important paralog of NPY2R is NPY1R

and can function as a cellular transcription factor

It forms a core complex with the 38 and 40 kDa subunits

A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers

which binds tropomyosin

FoxN4 Polyclonal Antibody, 50ul Culture Tubes An important paralog of NPY2RMembers of the winged helix forkhead family of transcription factors, such as FOXN4, are characterized by a 110 amino acid DNA binding domain that can fold into a variant of the helix turn helix motif consisting of 3 alpha helices flanked by 2 large loops or wings. These transcription factors are involved in a variety of biologic processes as key regulators in development and metabolism (Li et al. 2004 [PubMed 15363391]).