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It regulates circulating fetal thyroid hormone concentrations

with a recovery rate over 90%

Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified

Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease

DR4 Polyclonal Antibody, 20ul Hybridoma Antibody Sequencing Unleash its precision and accuracyTNF receptor superfamily member 10a encoded by TNFRSF10A is a member of the TNF receptor superfamily. This receptor is activated by tumor necrosis factor related apoptosis inducing ligand (TNFSF10 TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.