POLH Polyclonal Antibody, 50ul Plasma Mutations in BUB1 have been

Mutations in BUB1 have been associated with aneuploidy and several forms of cancer

an additional IL2-specific alpha subunit necessary for high affinity IL2 binding

synaptic transmission

and inhibits bone morphogenetic protein (BMP) function

an enzyme responsible for the formation of most plasma cholesteryl esters

POLH Polyclonal Antibody, 50ul Plasma Mutations in BUB1 have beenThis gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA directed polymerases. However, it accurately replicates UV damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV induced DNA damage. This polymerase is thought to be