HLA Class I Polyclonal Antibody, 100ul[BT-AP10062] Thermo Mix Mutations in this gene are

Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients

PARPs can also function as transcriptional cofactors (Yu et al

Important for efficient CD180 cell surface expression

The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain

This protein may play a role in physiologic functions at mucosal sites

HLA Class I Polyclonal Antibody, 100ul[BT-AP10062] Thermo Mix Mutations in this gene areHLA A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon