PDE1A Polyclonal Antibody, 50ul Micro Centrifuge Tubes The encoded protein localizes to

The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine

May be involved in apoptosis signaling in the presence of the reinoid CD437

such as Waardenburg syndrome type 2 and Tietz syndrome

RAB3GAP2 has the highest level of expression in the brain

Belongs to the heat shock protein 70 family

PDE1A Polyclonal Antibody, 50ul Micro Centrifuge Tubes The encoded protein localizes toCyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and or cGMP to their respective nucleoside 5 prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+) calmodulin (see CALM1; MIM 114180) dependent PDEs (CaM PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001