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Additionally, 67% of participants receiving GSBR-1290 achieved at least a 6% weight reduction, and 33% achieved at least a 10% weight reduction by week 12, while no participants in the placebo group achieved these benchmarks

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NICE guidance (NG28) recommends a stepwise approach to diabetes management, with treatment intensification based on individualised HbA1c targets, considering factors such as cardiovascular risk, renal function, patient preference, and cost-effectiveness