LTOR2 Polyclonal Antibody, 100ul CellSafe™ Mitogen-activated protein kinase kinase kinase

Mitogen-activated protein kinase kinase kinase 3 directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively

encoded by two different genes

and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription

Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha

Excellent transmittance of the PET membrane

LTOR2 Polyclonal Antibody, 100ul CellSafe™ Mitogen-activated protein kinase kinase kinaseThe product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding