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PPP1R3A Polyclonal Antibody, 100ul General Lab Use This gene encodes a preproprotein

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PPP1R3A Polyclonal Antibody, 100ul General Lab Use This gene encodes a preproproteinThe glycogen associated form of protein phosphatase 1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37 kD catalytic subunit and a 124 kD targeting and regulatory subunit. PPP1R3A (protein phosphatase 1 regulatory subunit 3A) encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase

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Description

This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products

Mutations in this gene cause Griscelli syndrome type-1 (GS1)

is a E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage

The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration

The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis

PPP1R3A Polyclonal Antibody, 100ul General Lab Use This gene encodes a preproproteinThe glycogen associated form of protein phosphatase 1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37 kD catalytic subunit and a 124 kD targeting and regulatory subunit. PPP1R3A (protein phosphatase 1 regulatory subunit 3A) encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase

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