PYGM Rabbit Polyclonal Antibody, 20ul Antibody Humanization Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include chromatin binding and nucleosome binding

including Burkitt lymphoma

The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues

an N-terminal DNA-binding domain| a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression

The encoded protein may be involved in suppressing tumor formation by regulating cell invasion and adhesion

PYGM Rabbit Polyclonal Antibody, 20ul Antibody Humanization Gene Ontology (GO) annotations relatedThis gene encodes a muscle enzyme involved in glycogenolysis. Highly similar enzymes encoded by different genes are found in liver and brain. Mutations in this gene are associated with McArdle disease (myophosphorylase deficiency) a glycogen storage disease of muscle. Alternative splicing results in multiple transcript variants.