ErbB-3 Polyclonal Antibody, 20ul[BT-AP03040] Immuno Plates The protein encoded by CNOT4

The protein encoded by CNOT4 is a subunit of the CCR4-NOT complex

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The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions

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CD6 product is important for continuation of T cell activation

ErbB-3 Polyclonal Antibody, 20ul[BT-AP03040] Immuno Plates The protein encoded by CNOT4ERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation