p27(Phospho Thr157) Polyclonal Antibody, 100ul Funnels Ubiquitin (MIM 191339) is a

Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown| cell cycle regulation| and stress response

The gene encoding this protein is localized to 11q12| among a cluster of related family members

As a member of the ERM protein family

and expressed in testis and in a significant fraction of tumors of various histological types

The tumor necrosis factor superfamily member 4 functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells

p27(Phospho Thr157) Polyclonal Antibody, 100ul Funnels Ubiquitin (MIM 191339) is aThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from