TGFA1 Polyclonal Antibody, 20ul Bottle-Top Dispenser The Ribosomal protein S6 kinase

The Ribosomal protein S6 kinase alpha-6 may be distinct from other members of this family

The encoded protein is expressed in endothelial cells

Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis

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Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC)

TGFA1 Polyclonal Antibody, 20ul Bottle-Top Dispenser The Ribosomal protein S6 kinaseThis gene encodes a protein that binds to transforming growth factor beta (TGF beta) receptors and plays a role in TGF beta signaling. The encoded protein acts as a chaprone in signaling downstream of TGF beta. It is involved in signal dependent association with SMAD4. The protein is also a component of mammalian CORVET, a multisubunit tethering protein complex that is involved in fusion of early endosomes.