MEK Kinase-1(Phospho Thr1402) Polyclonal Antibody, 20ul Custom DNA Oligos This PTP is widely expressed

This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions| such as mitogenic activation| metabolic control| transcription regulation| and cell migration

The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase

In vascular endothelial cells

The protein product of this gene

The protein encoded by this gene is a member of the immunoglobulin superfamily

MEK Kinase-1(Phospho Thr1402) Polyclonal Antibody, 20ul Custom DNA Oligos This PTP is widely expressedThe protein encoded by this gene is a serine threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF kappa B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N terminus and phospho kinase activity conferred by a